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Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed

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@article{IJASEIT571,
   author = {Maria Selvaggi and Fedrica Ioanna and Francesco Pinto and Cataldo Dario},
   title = {Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed},
   journal = {International Journal on Advanced Science, Engineering and Information Technology},
   volume = {5},
   number = {5},
   year = {2015},
   pages = {323--325},
   keywords = {STAT5A gene; single nucleotide polymorphism Garganica goat},
   abstract = {

STATs (signal transducer and activator of transcription) are a group of transcription factors that mediate actions of a variety of peptide hormones and cytokines within target cells (for example prolactin and growth hormone). In particular, STAT5A gene is a candidate marker for quantitative traits in farm animals. In this study, the STAT5A/Eco81I polymorphism was investigated with PCR-RFLP in a sample of Garganica goats. Garganica breed is an Italian goat breed that originates in the Gargano promontory, in Apulia region, by crossing the autochthonous population of goat with west European goats. Garganica breed show an exceptional ability to adapt to particularly difficult environments, as well as an extraordinary capacity to utilize poor pasture that would not otherwise be used. The investigated polymorphism is a substitution C→T at position 6852 within the exon 7 of the STAT5A gene. Only two out of three possible genotypes were identified in the population. The allelic frequencies of alleles C and T were 0.863 and 0.137 respectively and the population was kept in Hardy-Weinberg equilibrium. Moreover, some population genetic indices were also reported.

},    issn = {2088-5334},    publisher = {INSIGHT - Indonesian Society for Knowledge and Human Development},    url = {http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=571},    doi = {10.18517/ijaseit.5.5.571} }

EndNote

%A Selvaggi, Maria
%A Ioanna, Fedrica
%A Pinto, Francesco
%A Dario, Cataldo
%D 2015
%T Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed
%B 2015
%9 STAT5A gene; single nucleotide polymorphism Garganica goat
%! Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed
%K STAT5A gene; single nucleotide polymorphism Garganica goat
%X 

STATs (signal transducer and activator of transcription) are a group of transcription factors that mediate actions of a variety of peptide hormones and cytokines within target cells (for example prolactin and growth hormone). In particular, STAT5A gene is a candidate marker for quantitative traits in farm animals. In this study, the STAT5A/Eco81I polymorphism was investigated with PCR-RFLP in a sample of Garganica goats. Garganica breed is an Italian goat breed that originates in the Gargano promontory, in Apulia region, by crossing the autochthonous population of goat with west European goats. Garganica breed show an exceptional ability to adapt to particularly difficult environments, as well as an extraordinary capacity to utilize poor pasture that would not otherwise be used. The investigated polymorphism is a substitution C→T at position 6852 within the exon 7 of the STAT5A gene. Only two out of three possible genotypes were identified in the population. The allelic frequencies of alleles C and T were 0.863 and 0.137 respectively and the population was kept in Hardy-Weinberg equilibrium. Moreover, some population genetic indices were also reported.

%U http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=571 %R doi:10.18517/ijaseit.5.5.571 %J International Journal on Advanced Science, Engineering and Information Technology %V 5 %N 5 %@ 2088-5334

IEEE

Maria Selvaggi,Fedrica Ioanna,Francesco Pinto and Cataldo Dario,"Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed," International Journal on Advanced Science, Engineering and Information Technology, vol. 5, no. 5, pp. 323-325, 2015. [Online]. Available: http://dx.doi.org/10.18517/ijaseit.5.5.571.

RefMan/ProCite (RIS)

TY  - JOUR
AU  - Selvaggi, Maria
AU  - Ioanna, Fedrica
AU  - Pinto, Francesco
AU  - Dario, Cataldo
PY  - 2015
TI  - Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed
JF  - International Journal on Advanced Science, Engineering and Information Technology; Vol. 5 (2015) No. 5
Y2  - 2015
SP  - 323
EP  - 325
SN  - 2088-5334
PB  - INSIGHT - Indonesian Society for Knowledge and Human Development
KW  - STAT5A gene; single nucleotide polymorphism Garganica goat
N2  - 

STATs (signal transducer and activator of transcription) are a group of transcription factors that mediate actions of a variety of peptide hormones and cytokines within target cells (for example prolactin and growth hormone). In particular, STAT5A gene is a candidate marker for quantitative traits in farm animals. In this study, the STAT5A/Eco81I polymorphism was investigated with PCR-RFLP in a sample of Garganica goats. Garganica breed is an Italian goat breed that originates in the Gargano promontory, in Apulia region, by crossing the autochthonous population of goat with west European goats. Garganica breed show an exceptional ability to adapt to particularly difficult environments, as well as an extraordinary capacity to utilize poor pasture that would not otherwise be used. The investigated polymorphism is a substitution C→T at position 6852 within the exon 7 of the STAT5A gene. Only two out of three possible genotypes were identified in the population. The allelic frequencies of alleles C and T were 0.863 and 0.137 respectively and the population was kept in Hardy-Weinberg equilibrium. Moreover, some population genetic indices were also reported.

UR - http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=571 DO - 10.18517/ijaseit.5.5.571

RefWorks

RT Journal Article
ID 571
A1 Selvaggi, Maria
A1 Ioanna, Fedrica
A1 Pinto, Francesco
A1 Dario, Cataldo
T1 Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed
JF International Journal on Advanced Science, Engineering and Information Technology
VO 5
IS 5
YR 2015
SP 323
OP 325
SN 2088-5334
PB INSIGHT - Indonesian Society for Knowledge and Human Development
K1 STAT5A gene; single nucleotide polymorphism Garganica goat
AB 

STATs (signal transducer and activator of transcription) are a group of transcription factors that mediate actions of a variety of peptide hormones and cytokines within target cells (for example prolactin and growth hormone). In particular, STAT5A gene is a candidate marker for quantitative traits in farm animals. In this study, the STAT5A/Eco81I polymorphism was investigated with PCR-RFLP in a sample of Garganica goats. Garganica breed is an Italian goat breed that originates in the Gargano promontory, in Apulia region, by crossing the autochthonous population of goat with west European goats. Garganica breed show an exceptional ability to adapt to particularly difficult environments, as well as an extraordinary capacity to utilize poor pasture that would not otherwise be used. The investigated polymorphism is a substitution C→T at position 6852 within the exon 7 of the STAT5A gene. Only two out of three possible genotypes were identified in the population. The allelic frequencies of alleles C and T were 0.863 and 0.137 respectively and the population was kept in Hardy-Weinberg equilibrium. Moreover, some population genetic indices were also reported.

LK http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=571 DO - 10.18517/ijaseit.5.5.571