DOI : https://doi.org/10.18517/ijaseit.5.5.571

Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed

Maria Selvaggi (1), Fedrica Ioanna (2), Francesco Pinto (3), Cataldo Dario (4)
(1) Department of DETO, Section of Veterinary Science and Animal Production, University of Bari “Aldo Moro”, Valenzano 70010, Italy
(2) Department of DETO, Section of Veterinary Science and Animal Production, University of Bari “Aldo Moro”, Valenzano 70010, Italy
(3) Department of DETO, Section of Veterinary Science and Animal Production, University of Bari “Aldo Moro”, Valenzano 70010, Italy
(4) Department of DETO, Section of Veterinary Science and Animal Production, University of Bari “Aldo Moro”, Valenzano 70010, Italy
Fulltext View | Download
How to cite (IJASEIT) :
Selvaggi, Maria, et al. “Analysis of A Sequence Nucleotide Polymorphism of STAT5A Gene in Garganica Goat Breed”. International Journal on Advanced Science, Engineering and Information Technology, vol. 5, no. 5, Oct. 2015, pp. 323-5, doi:10.18517/ijaseit.5.5.571.
Citation Format :
STATs (signal transducer and activator of transcription) are a group of transcription factors that mediate actions of a variety of peptide hormones and cytokines within target cells (for example prolactin and growth hormone). In particular, STAT5A gene is a candidate marker for quantitative traits in farm animals. In this study, the STAT5A/Eco81I polymorphism was investigated with PCR-RFLP in a sample of Garganica goats. Garganica breed is an Italian goat breed that originates in the Gargano promontory, in Apulia region, by crossing the autochthonous population of goat with west European goats. Garganica breed show an exceptional ability to adapt to particularly difficult environments, as well as an extraordinary capacity to utilize poor pasture that would not otherwise be used. The investigated polymorphism is a substitution C→T at position 6852 within the exon 7 of the STAT5A gene. Only two out of three possible genotypes were identified in the population. The allelic frequencies of alleles C and T were 0.863 and 0.137 respectively and the population was kept in Hardy-Weinberg equilibrium. Moreover, some population genetic indices were also reported.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).