Optimization of Emulsification Process Parameters of Cinnamon Oil Nanoemulsions

Yuliani Aisyah (1), Sri Haryani (2), Novi Safriani (3), Nida El Husna (4)
(1) Department of Agricultural Product Technology, University Syiah Kuala, Banda Aceh, 23111, Indonesia
(2) Department of Agricultural Product Technology, University Syiah Kuala, Banda Aceh, 23111, Indonesia
(3) Department of Agricultural Product Technology, University Syiah Kuala, Banda Aceh, 23111, Indonesia
(4) Department of Agricultural Product Technology, University Syiah Kuala, Banda Aceh, 23111, Indonesia
Fulltext View | Download
How to cite (IJASEIT) :
Aisyah, Yuliani, et al. “Optimization of Emulsification Process Parameters of Cinnamon Oil Nanoemulsions”. International Journal on Advanced Science, Engineering and Information Technology, vol. 8, no. 5, Oct. 2018, pp. 2092-8, doi:10.18517/ijaseit.8.5.929.
Essential oil is a complex blend of a variety of volatile molecules such as terpenoids, phenol-derived aromatic components. Cinnamon oil (extracted from Cinnamon burmannii) with strong antibacterial properties which show low bioavailability due to its lipophilicity. The use of nanoemulsion-based formulations is one of several approaches found to be efficient in improving the bioavailability of lipophilic entities such as cinnamon oil. This study explores the effects of various emulsifying conditions on the physicochemical properties and stability evaluation of cinnamon oil nanoemulsion in order to optimize its production method. Cinnamon oil nanoemulsion prepared in various emulsifying conditions was evaluated for its effects on the physicochemical characteristics and stability for a period of 3 months. The optimal formulation obtained required 5 minutes and 12000 rpm pre-homogenizing speed, high pressure (500 bars) and 3 cycles with the composition of 20% surfactant, 15% cinnamon oil and 85% water. Cinnamon oil loaded in the optimal formulation were stable after the manufacturing process and storage at 4°C±2 °C, 28°C±2 °C  and 40°C±2 °C  for 3 months. The finding of this study will lead to the possibility of this formulation to be used as one of the methods to improve cinnamon oil bioavailability.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).