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Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study

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@article{IJASEIT14030,
   author = {Jaswantsing L. Rajput and Anil B. Nandgaonkar and Sanjay L. Nalbalwar and Abhay E. Wagh},
   title = {Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study},
   journal = {International Journal on Advanced Science, Engineering and Information Technology},
   volume = {11},
   number = {4},
   year = {2021},
   pages = {1281--1287},
   keywords = {Breast cancer; heat flow modeling; hyperthermia treatment (HT); tissue; tumor.},
   abstract = {Heating the tumor tissue with an optimized amount of microwave energy is a promising combinational therapy, called hyperthermia treatment (HT), used with chemotherapy and radiotherapy. This combinational therapy has shown improvement in the survivorship for patients, and life after treatment. In clinical practice, radiation oncologists are still not using HT as a standard therapy because of some side effects like toxicity and hotspots on the surrounding site. To address this issue, optimal focusing of microwave on tumors, with minimal damage of surrounding tissues, is essential to avoid the side effects of HT. Our article briefly discusses on optimal focusing of microwaves on a tumor, computational feasibility study, and analysis of hyperthermia treatment. For the achievement of best outcomes, electrostatic modeling and heat flow modeling of 2D female breast models with tumors have been carried out. The finite element method (FEM) is used to solve the bio-heat equation at the tumor domain, consisting of radiation and convection-based boundary conditions. Obtained simulation results show that the highest focusing of radiation power on and around the tumor inside the breast has been given higher efficiency for hyperthermia. Our 2D modeling simulation results are helpful for improving hyperthermia treatment of breast cancer patients, with minimal damage to cells in the surrounding. Also, the article includes a mathematical analysis of hyperthermia and FEM modeling results concerning temperature distribution, heat flow, electric field intensity, electric flux density, heat flux density, and temperature variations in the breast tumor.},
   issn = {2088-5334},
   publisher = {INSIGHT - Indonesian Society for Knowledge and Human Development},
   url = {http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=14030},
   doi = {10.18517/ijaseit.11.4.14030}
}

EndNote

%A Rajput, Jaswantsing L.
%A Nandgaonkar, Anil B.
%A Nalbalwar, Sanjay L.
%A Wagh, Abhay E.
%D 2021
%T Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study
%B 2021
%9 Breast cancer; heat flow modeling; hyperthermia treatment (HT); tissue; tumor.
%! Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study
%K Breast cancer; heat flow modeling; hyperthermia treatment (HT); tissue; tumor.
%X Heating the tumor tissue with an optimized amount of microwave energy is a promising combinational therapy, called hyperthermia treatment (HT), used with chemotherapy and radiotherapy. This combinational therapy has shown improvement in the survivorship for patients, and life after treatment. In clinical practice, radiation oncologists are still not using HT as a standard therapy because of some side effects like toxicity and hotspots on the surrounding site. To address this issue, optimal focusing of microwave on tumors, with minimal damage of surrounding tissues, is essential to avoid the side effects of HT. Our article briefly discusses on optimal focusing of microwaves on a tumor, computational feasibility study, and analysis of hyperthermia treatment. For the achievement of best outcomes, electrostatic modeling and heat flow modeling of 2D female breast models with tumors have been carried out. The finite element method (FEM) is used to solve the bio-heat equation at the tumor domain, consisting of radiation and convection-based boundary conditions. Obtained simulation results show that the highest focusing of radiation power on and around the tumor inside the breast has been given higher efficiency for hyperthermia. Our 2D modeling simulation results are helpful for improving hyperthermia treatment of breast cancer patients, with minimal damage to cells in the surrounding. Also, the article includes a mathematical analysis of hyperthermia and FEM modeling results concerning temperature distribution, heat flow, electric field intensity, electric flux density, heat flux density, and temperature variations in the breast tumor.
%U http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=14030
%R doi:10.18517/ijaseit.11.4.14030
%J International Journal on Advanced Science, Engineering and Information Technology
%V 11
%N 4
%@ 2088-5334

IEEE

Jaswantsing L. Rajput,Anil B. Nandgaonkar,Sanjay L. Nalbalwar and Abhay E. Wagh,"Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study," International Journal on Advanced Science, Engineering and Information Technology, vol. 11, no. 4, pp. 1281-1287, 2021. [Online]. Available: http://dx.doi.org/10.18517/ijaseit.11.4.14030.

RefMan/ProCite (RIS)

TY  - JOUR
AU  - Rajput, Jaswantsing L.
AU  - Nandgaonkar, Anil B.
AU  - Nalbalwar, Sanjay L.
AU  - Wagh, Abhay E.
PY  - 2021
TI  - Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study
JF  - International Journal on Advanced Science, Engineering and Information Technology; Vol. 11 (2021) No. 4
Y2  - 2021
SP  - 1281
EP  - 1287
SN  - 2088-5334
PB  - INSIGHT - Indonesian Society for Knowledge and Human Development
KW  - Breast cancer; heat flow modeling; hyperthermia treatment (HT); tissue; tumor.
N2  - Heating the tumor tissue with an optimized amount of microwave energy is a promising combinational therapy, called hyperthermia treatment (HT), used with chemotherapy and radiotherapy. This combinational therapy has shown improvement in the survivorship for patients, and life after treatment. In clinical practice, radiation oncologists are still not using HT as a standard therapy because of some side effects like toxicity and hotspots on the surrounding site. To address this issue, optimal focusing of microwave on tumors, with minimal damage of surrounding tissues, is essential to avoid the side effects of HT. Our article briefly discusses on optimal focusing of microwaves on a tumor, computational feasibility study, and analysis of hyperthermia treatment. For the achievement of best outcomes, electrostatic modeling and heat flow modeling of 2D female breast models with tumors have been carried out. The finite element method (FEM) is used to solve the bio-heat equation at the tumor domain, consisting of radiation and convection-based boundary conditions. Obtained simulation results show that the highest focusing of radiation power on and around the tumor inside the breast has been given higher efficiency for hyperthermia. Our 2D modeling simulation results are helpful for improving hyperthermia treatment of breast cancer patients, with minimal damage to cells in the surrounding. Also, the article includes a mathematical analysis of hyperthermia and FEM modeling results concerning temperature distribution, heat flow, electric field intensity, electric flux density, heat flux density, and temperature variations in the breast tumor.
UR  - http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=14030
DO  - 10.18517/ijaseit.11.4.14030

RefWorks

RT Journal Article
ID 14030
A1 Rajput, Jaswantsing L.
A1 Nandgaonkar, Anil B.
A1 Nalbalwar, Sanjay L.
A1 Wagh, Abhay E.
T1 Heat Flow Modeling for Controlled Focusing of Microwave Hyperthermia of Breast Cancer: a Computational Feasibility Study
JF International Journal on Advanced Science, Engineering and Information Technology
VO 11
IS 4
YR 2021
SP 1281
OP 1287
SN 2088-5334
PB INSIGHT - Indonesian Society for Knowledge and Human Development
K1 Breast cancer; heat flow modeling; hyperthermia treatment (HT); tissue; tumor.
AB Heating the tumor tissue with an optimized amount of microwave energy is a promising combinational therapy, called hyperthermia treatment (HT), used with chemotherapy and radiotherapy. This combinational therapy has shown improvement in the survivorship for patients, and life after treatment. In clinical practice, radiation oncologists are still not using HT as a standard therapy because of some side effects like toxicity and hotspots on the surrounding site. To address this issue, optimal focusing of microwave on tumors, with minimal damage of surrounding tissues, is essential to avoid the side effects of HT. Our article briefly discusses on optimal focusing of microwaves on a tumor, computational feasibility study, and analysis of hyperthermia treatment. For the achievement of best outcomes, electrostatic modeling and heat flow modeling of 2D female breast models with tumors have been carried out. The finite element method (FEM) is used to solve the bio-heat equation at the tumor domain, consisting of radiation and convection-based boundary conditions. Obtained simulation results show that the highest focusing of radiation power on and around the tumor inside the breast has been given higher efficiency for hyperthermia. Our 2D modeling simulation results are helpful for improving hyperthermia treatment of breast cancer patients, with minimal damage to cells in the surrounding. Also, the article includes a mathematical analysis of hyperthermia and FEM modeling results concerning temperature distribution, heat flow, electric field intensity, electric flux density, heat flux density, and temperature variations in the breast tumor.
LK http://ijaseit.insightsociety.org/index.php?option=com_content&view=article&id=9&Itemid=1&article_id=14030
DO  - 10.18517/ijaseit.11.4.14030